Effect of Chitosan on Rheological, Mechanical, and Adhesive Properties of Pectin–Calcium Gel

In the present study, chitosan was included in pectin ionotropic gel to improve its mechanical and bioadhesive properties. Pectin–chitosan gels P–Ch0, P–Ch1, P–Ch2, P–Ch3 of weight fractions 0.00, 0.25, 0.50, 0.75 were prepared characterized by dynamic rheological tests, penetration serosal adhesion ex vivo assays. The storage modulus (G′) loss (G″) values, hardness, elasticity P–Ch1 significantly higher than those P–Ch0 gel. However, a further increase content reduced these parameters. inclusion into led decrease an hardness during incubation Hanks’ solution at pH 5.0, 7.4, 8.0. P–Ch2 rat intestinal serosa 1.3 1.7 times stronger, whereas that similar Pre-incubation 5.0 7.4 adhesivity gels; however, exceeded P–Ch3. Thus, combined with stability wide range appeared be advantages